Applications of Hidden Markov Chains

Applications

A profile HMM modelling a multiple sequence alignment of proteins in Pfam

A profile HMM modelling a multiple sequence alignment of proteins in Pfam

HMMs can be applied in many fields where the goal is to recover a data sequence that is not immediately observable (but other data that depend on the sequence are). Applications include:

  • Computational finance
  • Single-molecule kinetic analysis
  • Neuroscience
  • Cryptanalysis
  • Speech recognition, including Siri
  • Speech synthesis
  • Part-of-speech tagging
  • Document separation in scanning solutions
  • Machine translation
  • Partial discharge
  • Gene prediction
  • Handwriting recognition
  • Alignment of bio-sequences
  • Time series analysis
  • Activity recognition
  • Protein folding
  • Sequence classification
  • Metamorphic virus detection
  • Sequence motif discovery (DNA and proteins)
  • DNA hybridization kinetics
  • Chromatin state discovery
  • Transportation forecasting
  • Solar irradiance variability