The beginning of the lecture is administrative, so you may skip to around 16:14. It introduces the concept of computational thinking. While the course is an introduction to programming, computational thinking applies to both software (via programming) and to hardware (via computer architecture). Pay particular attention to the computer block diagram, the program counter and the way instructions relate to the computer hardware.
Source: Eric Grimson and John Guttag, Massachusetts Institute of Technology, https://www.youtube.com/watch?v=k6U-i4gXkLM
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